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& Holbrook, N

4-HNE can form covalent bonds with proteins, DNA, and phospholipids, thereby disrupting cellular functions and playing a role in the pathogenesis of various diseases [144]

doi: 10.3390/molecules26030752 180 ManikM.SinghR

Am J Physiol 1998

Amine oxidase, copper containing 3 exerts anti-mesenchymal transformation and enhances CD4(+) T-cell recruitment to prolong survival in lung cancer

Antagonizing Ang II signaling with losartan partially prevents stress-induced myofibroblast activation, collagen accumulation, intimal hyperplasia, and aortic dilatation (121)